Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.52 |
| ▸ | ANPEP | P15144 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380241 | 1.00 | EPHX1 (0.56) | EPHX1KDM4ELMNAMAPK1SLC6A2 | |
| Hydrochloric Acid SCHEMBL5385721 | 0.98 | EPHX1 (0.54) | EPHX1KDM4ELMNAMAPK1SLC6A2 | |
| SCHEMBL10564045 | 0.80 | LOXL2 (0.44) | KDM4ELMNAMAPK1TAAR1MAOA | |
| Hydrochloric Acid SCHEMBL5378431 | 0.78 | LOXL2 (0.43) | KDM4ELMNAMAPK1TAAR1MAOA | |
| SCHEMBL7953179 | 0.78 | ANPEP (0.47) | EPHX1KDM4ELMNAMAPK1SLC6A2 | |
| SCHEMBL5113171 | 0.78 | ESR1 (0.58) | SLC6A2TAAR1SLC7A5 | |
| SCHEMBL6533959 | 0.78 | ALPI (0.53) | EPHX1KDM4ELMNAMAPK1SLC6A2 | |
| SCHEMBL11620748 | 0.78 | KDM4E (0.56) | EPHX1KDM4ELMNAMAPK1SLC6A2 | |
| SCHEMBL10253191 | 0.77 | SLC6A2 (0.58) | EPHX1KDM4ELMNAMAPK1SLC6A2 | |
| SCHEMBL5675489 | 0.77 | KDM4E (0.66) | EPHX1KDM4ELMNAMAPK1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013014287-A2 | DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE | CHIRON AS (NO) | 2013-01-31 | — | — | WO | claimed |
| EP-0910415-B1 | FLUORO-LABELLED ANTHRACYCLINE AND ANTHRACYCLINONE DERIVATIVES | PHARMACIA ITALIA SPA (IT) | 2004-05-12 | — | — | EP | claimed |
| JP-2000514784-A | — | — | 2000-11-07 | — | — | JP | claimed |
| US-6103700-A | FOR DIAGNOSING AMYLOIDOSIS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-08-15 | — | — | US | claimed |
| EP-0910415-A1 | FLUORO LABELLED ANTHRACYCLINONE AND ANTHRACYCLINE DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-04-28 | — | — | EP | claimed |
| WO-1997049433-A1 | FLUORO LABELLED ANTHRACYCLINONE AND ANTHRACYCLINE DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-12-31 | — | — | WO | claimed |
| US-20240368136-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-11-07 | — | — | US | disclosed |
| EP-3365334-B1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMA CO LTD (JP) | 2024-07-17 | — | — | EP | disclosed |
| US-11939321-B2 | Benzolactam compounds as protein kinase inhibitors | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-03-26 | — | — | US | disclosed |
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
| US-20220332695-A1 | UREA DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | RESEARCH TRIANGLE INSTITUTE | 2022-10-20 | — | — | US | disclosed |
| CN-115057883-A | Two-dimensional perovskite white light material and preparation method and application thereof | 吉林大学 | 2022-09-16 | — | — | CN | disclosed |
| CN-114948963-A | Protein kinase inhibitor benzolactam compounds | 大冢制药株式会社 | 2022-08-30 | — | — | CN | disclosed |
| EP-0910415-A1 | FLUORO LABELLED ANTHRACYCLINONE AND ANTHRACYCLINE DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1999-04-28 | — | — | EP | disclosed |
| WO-1997049433-A1 | FLUORO LABELLED ANTHRACYCLINONE AND ANTHRACYCLINE DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-12-31 | — | — | WO | disclosed |
| EP-0563132-B1 | TETRAPEPTIDE DERIVATIVES AND ANALOGUES | BLACK JAMES FOUNDATION (GB) | 1996-02-07 | — | — | EP | disclosed |
| US-5486597-A | GASTRIN ANTAGONIST AS ANTISECRETORY AGENTS OF GASTRIC JUICE FOR STOMACH CANCER | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-01-23 | — | — | US | disclosed |
| EP-0563132-A1 | TETRAPEPTIDE DERIVATIVES AND ANALOGUES. | BLACK JAMES FOUNDATION (GB) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011284-A1 | TETRAPEPTIDE DERIVATIVES AND ANALOGUES | THE JAMES BLACK FOUNDATION LIMITED (GB) | 1992-07-09 | — | — | WO | disclosed |
| US-3956333-A | BACTERICIDE | STERLING DRUG INC. (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11939321-B2 | Benzolactam compounds as protein kinase inhibitors | MAPK1, ALK, MAP3K1 | EPHX1 3246/4885KDM4E 1101/4885LMNA 816/4885 |
| US-20230019032-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | MAPK1, ALK, MAP3K1 | EPHX1 3246/4885KDM4E 1101/4885LMNA 816/4885 |
| US-20240368136-A1 | BENZOLACTAM COMPOUNDS AS PROTEIN KINASE INHIBITORS | MAPK1, ALK, MAP3K1 | EPHX1 3243/4885KDM4E 1095/4885LMNA 820/4885 |
| US-20220332695-A1 | UREA DERIVATIVES AS CB1 ALLOSTERIC MODULATORS | CNR1, CNR2, GPR119 | EPHX1 1999/4885KDM4E 935/4885LMNA 4623/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.