Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.84 |
| ▸ | PPARD | Q03181 | 8/20 | 0.84 |
| ▸ | PPARG | P37231 | 7/20 | 0.81 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.81 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.81 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.81 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.81 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.81 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381889 | 0.92 | PPARA (0.76) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6505836 | 0.91 | PPARA (0.81) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6375757 | 0.90 | PPARA (1.00) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6374864 | 0.89 | PPARA (1.00) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL3945771 | 0.89 | PPARA (1.00) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL5974634 | 0.89 | PPARA (0.74) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL5974713 | 0.89 | PPARA (0.82) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6503254 | 0.88 | PPARA (0.85) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6494122 | 0.88 | PPARA (1.00) | PPARAPPARDPPARGPSEN1PSEN2 | |
| SCHEMBL6494410 | 0.88 | PPARA (0.83) | PPARAPPARDPPARGPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2005514452-A | — | — | 2005-05-19 | — | — | JP | claimed |
| US-20050032787-A1 | Pheny (alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity | SIGMA-TAU INDUSTRIES FARMACEUTICHE RIUNITE S.P.A. (IT) | 2005-02-10 | — | — | US | claimed |
| EP-1465858-A2 | PHENY(ALKYL)CARBOXYLIC ACID DERIVATIVES AND DIONIC PHENYLALKYLHETEROCYCLIC DERIVATIVES AND THEIR USE AS MEDICINES WITH SERUM GLUCOSE AND/OR SERUM LIPID LOWERING ACTIVITY | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2004-10-13 | — | — | EP | claimed |
| WO-2003059864-A2 | PHENY(ALKYL)CARBOXYLIC ACID DERIVATIVES AND DIONIC PHENYLALKYLHETEROCYCLIC DERIVATIVES AND THEIR USE AS MEDICINES WITH SERUM GLUCOSE AND/OR SERUM LIPID LOWERING ACTIVITY | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-07-24 | — | — | WO | claimed |
| US-20050032787-A1 | Pheny (alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity | SIGMA-TAU INDUSTRIES FARMACEUTICHE RIUNITE S.P.A. (IT) | 2005-02-10 | — | — | US | disclosed |
| EP-1465858-A2 | PHENY(ALKYL)CARBOXYLIC ACID DERIVATIVES AND DIONIC PHENYLALKYLHETEROCYCLIC DERIVATIVES AND THEIR USE AS MEDICINES WITH SERUM GLUCOSE AND/OR SERUM LIPID LOWERING ACTIVITY | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003059864-A2 | PHENY(ALKYL)CARBOXYLIC ACID DERIVATIVES AND DIONIC PHENYLALKYLHETEROCYCLIC DERIVATIVES AND THEIR USE AS MEDICINES WITH SERUM GLUCOSE AND/OR SERUM LIPID LOWERING ACTIVITY | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032787-A1 | Pheny (alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity | LIPC, CPT1A, GPR119 | PPARA 83/4885PPARD 132/4885PPARG 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.