⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11103519 | 0.73 | — | — | |
| SCHEMBL7789814 | 0.66 | KMT2A (0.32) | — | |
| SCHEMBL8598523 | 0.63 | — | — | |
| SCHEMBL10521310 | 0.63 | GAA (0.47) | — | |
| SCHEMBL1267744 | 0.62 | — | — | |
| SCHEMBL31491478 | 0.62 | PLA2G7 (0.36) | — | |
| Iodide SCHEMBL11383402 | 0.61 | — | — | |
| SCHEMBL10518622 | 0.59 | CYP2A6 (0.45) | — | |
| SCHEMBL21901536 | 0.58 | CYP11B2 (0.38) | — | |
| SCHEMBL2541407 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027362-B1 | 2-HALO-6-O-SUBSTITUTED KETOLIDE DERIVATIVES | ABBOTT LAB (US) | 2005-06-29 | — | — | EP | disclosed |
| US-6124269-A | NOVEL ERYTHROMYCIN DERIVATIVE ANTIBIOTIC EFFECTIVE AGAINST GRAM-NEGATIVE BACTERIA AND HAVING LESS POTENTIAL FOR DEVELOPING BACTERIAL DRUG RESISTANCE | ABBOTT LABORATORIES (US) | 2000-09-26 | — | — | US | disclosed |