⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11417385 | 0.80 | ALDH1A1 (0.38) | — | |
| SCHEMBL635418 | 0.80 | — | — | |
| SCHEMBL1118146 | 0.80 | — | — | |
| SCHEMBL3114905 | 0.80 | — | — | |
| SCHEMBL1170405 | 0.79 | — | — | |
| Ethane SCHEMBL27863509 | 0.78 | ALDH1A1 (0.42) | — | |
| Methyl Alcohol SCHEMBL14764243 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL11007614 | 0.77 | LMNA (0.42) | — | |
| SCHEMBL1170561 | 0.76 | ALDH1A1 (0.42) | — | |
| SCHEMBL2799546 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976734-B1 | Selective inhibitors of viral or bacterial neuraminidase | GILEAD SCIENCES INC (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20050176758-A1 | 2-(hydroxy or methoxymethoxy)-4-(carboxy or alkoxycarbonyl)-5-(fluoro or hydrogen)-7-oxabicyclo(4.1.0)hept-3-ene chemical intermediates to neuraminidase inhibitors | GILEAD SCIENCES, INC. | 2005-08-11 | — | — | US | disclosed |
| US-6225341-B1 | FOR INHIBITING NEURAMINIDASE; FOR THERAPY AND PROPHYLAXIS OF VIRUS INFECTION | GILEAD SCIENCES, INC. | 2001-05-01 | — | — | US | disclosed |
| EP-0759917-B1 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | GILEAD SCIENCES INC (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1996026933-A9 | NOVEL SELECTIVE INHIBITORS OF VIRAL OR BACTERIAL NEURAMINIDASES | — | 1996-11-28 | — | — | WO | disclosed |
| US-4342711-A | EXTRUDING A SPINNING SOLUTION OF POLYMER AND SOLVENT AROUND A STREAM OF SOLVENT AND SWELLING LIQUID; INTO AN AQUEOUS BATH HIGH SPEED | NIPPON ZEON CO., LTD. (JP) | 1982-08-03 | — | — | US | disclosed |
| US-4323627-A | CONTROLLED HYDROLYSI USING ALKALI OR ACID | NIPPON ZEON CO., LTD. (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4322381-A | Method of manufacturing hollow fiber | NIPPON ZEON CO., LTD. (JP) | 1982-03-30 | — | — | US | disclosed |