Sulfuric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	HRH3	Q9Y5N1	1/20	0.42

▸	FFAR1	O14842	2/20	0.41

▸	AVPR1B	P47901	1/20	0.41

▸	NPC1	O15118	2/20	0.39

▸	RAB9A	P51151	2/20	0.39

▸	SMN1; SMN2	Q16637	2/20	0.39

▸	KDM4E	B2RXH2	1/20	0.39

▸	ALDH1A1	P00352	1/20	0.39

▸	CPT2	P23786	1/20	0.39

▸	CPT1A	P50416	1/20	0.39

▸	CPT1B	Q92523	1/20	0.39

▸	MRGPRX4	Q96LA9	1/20	0.39

▸	ADAMTS4	O75173	1/20	0.39

▸	MMP2	P08253	1/20	0.39

▸	MMP13	P45452	1/20	0.39

▸	MMP14	P50281	1/20	0.39

▸	ADAMTS5	Q9UNA0	1/20	0.39

▸	TRPM8	Q7Z2W7	1/20	0.39

▸	MEN1	O00255	2/20	0.39

▸	KMT2A	Q03164	2/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5585781	0.98	HRH3 (0.41)	HRH3FFAR1AVPR1BNPC1RAB9A
SCHEMBL5999838	0.97	HRH3 (0.44)	HRH3FFAR1AVPR1BNPC1RAB9A
SCHEMBL5585466	0.97	HRH3 (0.44)	HRH3FFAR1AVPR1BNPC1RAB9A
SCHEMBL5585509	0.96	HRH3 (0.44)	HRH3FFAR1AVPR1BNPC1RAB9A
Hydrochloric Acid SCHEMBL5585627	0.96	HRH3 (0.44)	HRH3FFAR1AVPR1BNPC1RAB9A
SCHEMBL5585799	0.96	HRH3 (0.44)	HRH3FFAR1AVPR1BNPC1RAB9A
Tromethamine SCHEMBL5585771	0.92	HRH3 (0.41)	HRH3FFAR1AVPR1BNPC1RAB9A
Sulfuric Acid SCHEMBL5585551	0.89	RXRA (0.40)	AVPR1BRAB9AKDM4ETRPM8MEN1
SCHEMBL5585787	0.89	HRH3 (0.39)	HRH3FFAR1AVPR1BSMN1; SMN2ALDH1A1
SCHEMBL5585507	0.89	HRH3 (0.41)	HRH3FFAR1SMN1; SMN2ALDH1A1ADAMTS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20050065196-A1	Azole compound and medicinal use thereof	JAPAN TOBACCO INC. (JP)	2005-03-24	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20050065196-A1	Azole compound and medicinal use thereof	PTPN7, PTPN1, PTPN5	HRH3 840/4885FFAR1 868/4885AVPR1B 3323/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.