Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VSIR | Q9H7M9 | 8/20 | 0.57 |
| ▸ | PARP1 | P09874 | 10/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380064 | 0.90 | PARP1 (0.54) | VSIRPARP1GRIN2BHPSE | |
| SCHEMBL6385598 | 0.88 | PARP1 (0.56) | VSIRPARP1HPSE | |
| SCHEMBL6379906 | 0.86 | PARP1 (0.49) | VSIRPARP1HPSE | |
| SCHEMBL7140549 | 0.85 | PARP1 (0.69) | VSIRPARP1 | |
| SCHEMBL6378984 | 0.84 | PARP1 (0.51) | VSIRPARP1HPSE | |
| SCHEMBL6383675 | 0.83 | PARP1 (0.57) | VSIRPARP1 | |
| SCHEMBL6379926 | 0.82 | PARP1 (0.58) | VSIRPARP1 | |
| SCHEMBL6380476 | 0.82 | PARP1 (0.72) | VSIRPARP1 | |
| SCHEMBL6380066 | 0.81 | PARP1 (0.55) | VSIRPARP1 | |
| SCHEMBL6383270 | 0.80 | PARP1 (0.51) | VSIRPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131301-B1 | 2-PHENYLBENZIMIDAZOLES AND 2-PHENYLINDOLES, AND PRODUCTION AND USE THEREOF | ABBOTT GMBH & CO KG (DE) | 2005-08-24 | — | — | EP | disclosed |