Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 19/20 | 0.69 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.60 |
| ▸ | DHODH | Q02127 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30811249 | 0.89 | PARP1 (0.76) | PARP1DHODH | |
| SCHEMBL29180029 | 0.89 | PARP1 (0.76) | PARP1DHODH | |
| SCHEMBL7137721 | 0.87 | PARP1 (0.79) | PARP1DHODH | |
| SCHEMBL6381122 | 0.85 | VSIR (0.57) | PARP1VSIR | |
| SCHEMBL29180021 | 0.83 | PARP1 (0.73) | PARP1DHODH | |
| SCHEMBL7141034 | 0.83 | PARP1 (0.72) | PARP1DHODH | |
| SCHEMBL7135042 | 0.82 | PARP1 (0.82) | PARP1DHODH | |
| SCHEMBL7138597 | 0.81 | PARP1 (0.80) | PARP1DHODH | |
| SCHEMBL7134234 | 0.81 | PARP1 (1.00) | PARP1DHODH | |
| SCHEMBL7136544 | 0.80 | PARP1 (0.78) | PARP1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6509365-B1 | 2-phenylbenzimidazoles and 2-phenylindoles, and production and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-21 | — | — | US | disclosed |