Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22906170 | 0.77 | NOTUM (0.55) | TSHRALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL31672516 | 0.77 | TSHR (0.56) | TSHRALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL22534127 | 0.73 | SMN1; SMN2 (0.58) | TSHRALDH1A1KMT2AHPGDLMNA | |
| SCHEMBL14454111 | 0.73 | TSHR (0.62) | TSHRALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL6382766 | 0.72 | ALDH1A1 (0.60) | TSHRALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL1032002 | 0.72 | MAPK1 (0.77) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL22754848 | 0.72 | KDM4E (0.55) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL2736551 | 0.71 | MEN1 (0.60) | TSHRALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL29446127 | 0.71 | NOTUM (0.61) | LMNAMAPTNPC1HTTNOTUM | |
| SCHEMBL7183285 | 0.70 | KMT2A (0.71) | TSHRKMT2AHPGDLMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059824-A1 | Method for catalyzing amidation reactions | PHARMACIA & UPJOHN COMPANY | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059824-A1 | Method for catalyzing amidation reactions | NIT2, C5, CCNT2 | TSHR 802/4885ALDH1A1 3748/4885KMT2A 1857/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.