Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6385468 | 0.85 | ACHE (0.59) | ACHEALDH1A1KDM4EHPGDGAA | |
| SCHEMBL6384868 | 0.82 | KDM4E (0.56) | ACHEALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL9370579 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EKMT2AHPGDGAA | |
| SCHEMBL6378695 | 0.80 | ACHE (0.57) | ACHEALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL6383120 | 0.80 | ACHE (0.57) | ACHEALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL10789768 | 0.80 | ALDH1A1 (0.57) | ACHEALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL23857155 | 0.79 | ALDH1A1 (0.52) | ACHEALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL6385452 | 0.77 | KDM4E (0.57) | ACHEALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL2062216 | 0.77 | CYP1A2 (0.48) | ALDH1A1KDM4EKMT2AHPGDGAA | |
| SCHEMBL31143068 | 0.77 | PDE4A (0.40) | ALDH1A1KDM4EKMT2AHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047674-B1 | PROCESS FOR PRODUCTION OF DONEPEZIL DERIVATIVES | EISAI CO LTD (JP) | 2005-03-30 | — | — | EP | disclosed |
| EP-1047674-A1 | PROCESS FOR PRODUCTION OF DONEPEZIL DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999036405-A1 | PROCESS FOR PRODUCTION OF DONEPEZIL DERIVATIVE | EISAI CO., LTD. (JP) | 1999-07-22 | — | — | WO | disclosed |