Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 6/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | STK4 | Q13043 | 4/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | STK3 | Q13188 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381772 | 0.82 | EGFR (0.56) | EGFRERBB2SRCSTK4 | |
| SCHEMBL6385221 | 0.79 | STK4 (0.55) | EGFRERBB2SRCSTK4 | |
| SCHEMBL6385203 | 0.78 | SRC (0.47) | EGFRERBB2ALDH1A1SRC | |
| SCHEMBL6383733 | 0.77 | PDE5A (0.47) | EGFRERBB2SRC | |
| SCHEMBL6386181 | 0.77 | EGFR (0.43) | EGFRERBB2SRCSTK4 | |
| SCHEMBL6384516 | 0.73 | EGFR (0.54) | EGFRERBB2SRCSTK4 | |
| SCHEMBL6382237 | 0.72 | EGFR (0.58) | PRKCQEGFRERBB2SRCSTK4 | |
| SCHEMBL6383793 | 0.72 | EGFR (0.58) | PRKCQEGFRERBB2SRCSTK4 | |
| SCHEMBL6383932 | 0.72 | EGFR (0.70) | PRKCQEGFRERBB2 | |
| SCHEMBL6383971 | 0.70 | STK4 (0.55) | EGFRERBB2ALDH1A1SRCSTK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263503-B1 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | WYETH CORP (US) | 2005-11-02 | — | — | EP | claimed |
| EP-0973746-B1 | SUBSTITUTED 3-CYANO QUINOLINES | WYETH CORP (US) | 2003-09-24 | — | — | EP | claimed |