Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK4 | Q13043 | 2/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382054 | 0.80 | STK4 (0.73) | STK4LRRK2EGFRERBB2SRC | |
| SCHEMBL6385221 | 0.76 | STK4 (0.55) | STK4EGFRERBB2SRC | |
| SCHEMBL7002420 | 0.75 | STK4 (0.34) | STK4SLC6A3EGFRERBB2ALDH1A1 | |
| SCHEMBL22419654 | 0.71 | STK4 (1.00) | STK4LRRK2EGFRERBB2 | |
| SCHEMBL6383103 | 0.70 | PRKCQ (0.39) | STK4EGFRERBB2ALDH1A1SRC | |
| SCHEMBL27460476 | 0.69 | EGFR (0.61) | STK4LRRK2EGFRERBB2SRC | |
| SCHEMBL6384516 | 0.68 | EGFR (0.54) | STK4EGFRERBB2SRC | |
| SCHEMBL6382237 | 0.68 | EGFR (0.58) | STK4EGFRERBB2SRC | |
| SCHEMBL6383793 | 0.68 | EGFR (0.58) | STK4EGFRERBB2SRC | |
| SCHEMBL27480999 | 0.67 | STK4 (0.55) | STK4EGFRERBB2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263503-B1 | USE OF CYANOQUINOLINES FOR TREATING OR INHIBITING COLONIC POLYPS | WYETH CORP (US) | 2005-11-02 | — | — | EP | claimed |
| EP-0973746-B1 | SUBSTITUTED 3-CYANO QUINOLINES | WYETH CORP (US) | 2003-09-24 | — | — | EP | claimed |