⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380424 | 0.75 | ADORA2A (0.43) | — | |
| SCHEMBL6735249 | 0.75 | PRMT5 (0.35) | — | |
| SCHEMBL4797338 | 0.75 | PRMT5 (0.35) | — | |
| SCHEMBL6840048 | 0.73 | MGLL (0.33) | — | |
| SCHEMBL1737148 | 0.73 | PRMT5 (0.39) | — | |
| SCHEMBL1740336 | 0.73 | ADORA2A (0.32) | — | |
| SCHEMBL3286808 | 0.71 | ADK (0.42) | — | |
| SCHEMBL6839945 | 0.70 | PRMT5 (0.32) | — | |
| SCHEMBL1737327 | 0.70 | PRMT5 (0.41) | — | |
| SCHEMBL5533308 | 0.70 | IDO1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501850-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003093290-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2003-11-13 | — | — | WO | disclosed |