Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6383692 | 0.92 | DPP4 (0.42) | DPP4L3MBTL1ALDH1A1LMNAHTR2A | |
| Trifluoroacetic Acid SCHEMBL5719238 | 0.90 | DPP4 (0.52) | DPP4L3MBTL1ALDH1A1LMNAHTR2A | |
| SCHEMBL6383694 | 0.87 | DPP4 (0.40) | DPP4L3MBTL1ALDH1A1LMNAFAP | |
| Trifluoroacetic Acid SCHEMBL5773381 | 0.85 | DPP4 (0.46) | DPP4L3MBTL1ALDH1A1LMNAFAP | |
| Trifluoroacetic Acid SCHEMBL5719367 | 0.84 | DPP4 (0.45) | DPP4L3MBTL1ALDH1A1LMNAFAP | |
| Trifluoroacetic Acid SCHEMBL5719346 | 0.84 | LMNA (0.46) | DPP4L3MBTL1ALDH1A1LMNAHTR2A | |
| Trifluoroacetic Acid SCHEMBL5770326 | 0.83 | DPP4 (0.42) | DPP4L3MBTL1ALDH1A1LMNAHTR2A | |
| Trifluoroacetic Acid SCHEMBL5719045 | 0.82 | DPP4 (0.53) | DPP4L3MBTL1ALDH1A1LMNAHTR2A | |
| Trifluoroacetic Acid SCHEMBL6384005 | 0.82 | DPP4 (0.47) | DPP4L3MBTL1ALDH1A1LMNAFAP | |
| SCHEMBL5789166 | 0.81 | DPP4 (0.58) | DPP4L3MBTL1ALDH1A1LMNAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1557165-A1 | COMBINATION DRUG | Eisai Co., Ltd. (JP) | 2005-07-27 | — | — | EP | disclosed |