Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.56 |
| ▸ | MLNR | O43193 | 7/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | UBE2M | P61081 | 1/20 | 0.52 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5871316 | 0.90 | KDM4E (0.69) | KDM4EKMT2AALDH1A1POLBROCK2 | |
| SCHEMBL330906 | 0.82 | ALDH1A1 (0.63) | KDM4EKMT2AALDH1A1POLBROCK2 | |
| SCHEMBL330905 | 0.82 | ALDH1A1 (0.63) | KDM4EKMT2AALDH1A1POLBROCK2 | |
| SCHEMBL7294507 | 0.79 | KDM4E (0.64) | KDM4EKMT2AALDH1A1POLBROCK2 | |
| SCHEMBL924357 | 0.78 | ACHE (0.68) | KDM4EKMT2AALDH1A1POLBROCK2 | |
| SCHEMBL7286870 | 0.77 | KDM4E (0.67) | KDM4EKMT2AALDH1A1POLBROCK2 | |
| SCHEMBL8246483 | 0.77 | KDM4E (0.59) | KDM4EKMT2AALDH1A1POLBMLNR | |
| SCHEMBL1704373 | 0.77 | MLNR (0.80) | MLNRCYP3A4CYP2D6KCNH2 | |
| SCHEMBL1818246 | 0.77 | KDM4E (0.66) | KDM4EKMT2AALDH1A1POLBSIGMAR1 | |
| SCHEMBL5871587 | 0.77 | KDM4E (0.52) | KDM4EKMT2AMLNRCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556045-A1 | 4-AMINOPIPERIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB, S.A. (BE) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004030668-A1 | 4-AMINOPIPERIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | UCB, S.A. (BE) | 2004-04-15 | — | — | WO | disclosed |