Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380330 | 0.81 | HRH4 (0.39) | HRH4 | |
| SCHEMBL6381734 | 0.67 | KDM4E (0.39) | ADORA2AKDM4E | |
| SCHEMBL6378951 | 0.67 | MAPT (0.43) | KDM4E | |
| SCHEMBL6838307 | 0.66 | ADORA2A (0.47) | ADORA2AKDM4E | |
| SCHEMBL6380936 | 0.63 | ADORA2A (0.40) | ADORA2A | |
| SCHEMBL7600407 | 0.62 | ADORA2A (0.38) | ADORA2AKDM4E | |
| SCHEMBL6424493 | 0.60 | ATP1A1 (0.35) | ADORA2A | |
| SCHEMBL30504020 | 0.59 | GAA (0.33) | ADORA2A | |
| SCHEMBL1353956 | 0.59 | PARP1 (0.59) | HRH4KDM4E | |
| SCHEMBL12777898 | 0.59 | ALDH1A1 (0.42) | HRH4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501850-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2005-02-02 | — | — | EP | claimed |
| WO-2003093290-A2 | NUCLEOSIDE DERIVATIVES FOR TREATING HEPATITIS C VIRUS INFECTION | GENELABS TECHNOLOGIES, INC. (US) | 2003-11-13 | — | — | WO | claimed |