Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5747380 | 1.00 | BACE1 (0.31) | BACE1 | |
| SCHEMBL6604249 | 0.89 | MEN1 (0.32) | — | |
| SCHEMBL9870670 | 0.89 | MEN1 (0.32) | — | |
| SCHEMBL9865636 | 0.89 | MEN1 (0.32) | — | |
| SCHEMBL5505248 | 0.89 | — | — | |
| SCHEMBL2603209 | 0.74 | CRBN (0.33) | BACE1 | |
| SCHEMBL4378128 | 0.71 | IRAK4 (0.37) | — | |
| SCHEMBL4378117 | 0.71 | IRAK4 (0.37) | — | |
| SCHEMBL7624743 | 0.70 | ALDH1A1 (0.40) | BACE1 | |
| SCHEMBL11233543 | 0.70 | CRBN (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585729-A1 | 2-PIPERIDONE DERIVATIVES AS PROSTAGLANDIN AGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004063158-A1 | 2-PIPERIDONE DERIVATIVES AS PROSTAGLANDIN AGONISTS | F.HOFFMANN-LA ROCHE AG (CH) | 2004-07-29 | — | — | WO | disclosed |