Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 5/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MERTK | Q12866 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6463 | 0.85 | VCAM1 (1.00) | VCAM1MAPK1MERTKMAPTTDP1 | |
| SCHEMBL12253372 | 0.85 | VCAM1 (1.00) | VCAM1MAPK1MERTKMAPTTDP1 | |
| SCHEMBL10348032 | 0.83 | TSHR (0.60) | VCAM1MAPK1TSHRMERTKCA1 | |
| SCHEMBL4477143 | 0.82 | VCAM1 (0.70) | VCAM1MAPK1TSHRMERTKMAPT | |
| SCHEMBL16954831 | 0.81 | TSHR (0.58) | VCAM1MAPK1TSHRMERTKCA1 | |
| SCHEMBL4385438 | 0.79 | VCAM1 (0.61) | VCAM1MAPK1MERTKMAPTTDP1 | |
| SCHEMBL16792385 | 0.79 | MERTK (0.55) | VCAM1MAPK1TSHRMERTKMAPT | |
| SCHEMBL16387399 | 0.79 | VCAM1 (0.66) | VCAM1MAPK1TSHRMERTKMAPT | |
| SCHEMBL14220808 | 0.78 | VCAM1 (0.59) | VCAM1MAPK1MERTKMAPTTDP1 | |
| SCHEMBL1511983 | 0.78 | VCAM1 (0.59) | VCAM1MAPK1MERTKMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080074-A | Tetradentate ring metal platinum (II) complex and organic electroluminescent device comprising same | — | 2026-05-26 | — | — | CN | disclosed |
| CN-118666780-A | Method for preparing morpholinosulfonamide compound by microwave promotion | 邵阳学院 | 2024-09-20 | — | — | CN | disclosed |
| CN-116120190-B | Method for preparing o-nitroaniline compound and application of o-nitroaniline compound | 邵阳学院 | 2024-08-23 | — | — | CN | disclosed |
| CN-116120190-A | Method for preparing o-nitroaniline compound and application of o-nitroaniline compound | 邵阳学院 | 2023-05-16 | — | — | CN | disclosed |
| EP-3490552-B1 | SELECTIVE BROMODOMAIN INHIBITION OF FUNGAL BDF1 | UNIV SOUTHERN CALIFORNIA (US) | 2022-11-23 | — | — | EP | disclosed |
| US-10918647-B2 | Selective bromodomain inhibition of fungal Bdf1 | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2021-02-16 | — | — | US | disclosed |
| US-20190240232-A1 | SELECTIVE BROMODOMAIN INHIBITION OF FUNGAL BDF1 | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2019-08-08 | — | — | US | disclosed |
| EP-3490552-A1 | SELECTIVE BROMODOMAIN INHIBITION OF FUNGAL BDF1 | University of Southern California (US) | 2019-06-05 | — | — | EP | disclosed |
| WO-2018022802-A1 | SELECTIVE BROMODOMAIN INHIBITION OF FUNGAL BDF1 | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 2018-02-01 | — | — | WO | disclosed |
| EP-2493310-A1 | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | GlaxoSmithKline LLC (US) | 2012-09-05 | — | — | EP | disclosed |
| WO-2002032422-A2 | EP4 RECEPTOR INHIBITORS TO TREAT RHEUMATOID ARTHRITIS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-04-25 | — | — | WO | disclosed |
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| CN-1019388-B | Process for preparing N-alkylsulfonamide derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-12-09 | — | — | CN | disclosed |
| EP-0273369-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| US-4866091-A | ANTINFLAMMATORY AGENTS, ANALGESICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-12 | — | — | US | disclosed |
| CN-88103277-A | Novel N-alkane sulfonyl aniline derivatives and preparation method thereof and the pharmaceutical composition that comprises this material | — | 1988-12-07 | — | — | CN | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |
| CN-87108295-A | New alkane sulfonyl aniline derivative and its medicinal compositions and preparation method | — | 1988-07-13 | — | — | CN | disclosed |
| EP-0273369-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10918647-B2 | Selective bromodomain inhibition of fungal Bdf1 | BRPF3, BRD3, BRD1 | VCAM1 4067/4885MAPK1 945/4885TSHR 4529/4885 |
| US-20190240232-A1 | SELECTIVE BROMODOMAIN INHIBITION OF FUNGAL BDF1 | BRPF3, BRD3, BRD1 | VCAM1 4067/4885MAPK1 945/4885TSHR 4529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.