⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786534 | 0.63 | — | — | |
| SCHEMBL6307532 | 0.60 | — | — | |
| SCHEMBL8387545 | 0.59 | — | — | |
| SCHEMBL4544354 | 0.55 | — | — | |
| SCHEMBL747701 | 0.55 | — | — | |
| SCHEMBL30149879 | 0.52 | APAF1 (0.37) | — | |
| SCHEMBL27938127 | 0.52 | — | — | |
| Methyl Alcohol SCHEMBL27954457 | 0.49 | CA2 (0.40) | — | |
| SCHEMBL23785125 | 0.49 | — | — | |
| SCHEMBL10522865 | 0.49 | MAPT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539164-A1 | 2-HYDROXY-6-PHENYLPHENANTHRIDINES AS PDE-4 INHIBITORS | ALTANA Pharma AG (DE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004019944-A1 | 2-HYDROXY-6-PHENYLPHENANTHRIDINES AS PDE-4 INHIBITORS | ALTANA PHARMA AG (DE) | 2004-03-11 | — | — | WO | claimed |