Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 6/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4970290 | 0.83 | HTR2C (0.46) | MEN1KMT2AHTR2CHTR2AHTR2B | |
| SCHEMBL4721571 | 0.83 | HTR2C (0.46) | MEN1KMT2AHTR2CHTR2AHTR2B | |
| SCHEMBL3174801 | 0.81 | HTR2C (0.45) | MEN1KMT2AHTR2CLMNATSHR | |
| SCHEMBL4720346 | 0.79 | ALDH1A1 (0.44) | MEN1KMT2AHTR2CHTR1DLMNA | |
| SCHEMBL3165666 | 0.78 | HTR2C (0.47) | MEN1KMT2AHTR2CTSHRHTR2A | |
| SCHEMBL4720767 | 0.77 | HTR1D (0.48) | HTR2CHTR1DLMNATSHRMAPK1 | |
| SCHEMBL12313576 | 0.76 | ADRA2A (0.58) | ADRA2AADRA2BADRA2CHTR1AATM | |
| SCHEMBL4723202 | 0.75 | HTR1D (0.49) | ATMHTR2CHTR1DLMNATSHR | |
| SCHEMBL4724844 | 0.74 | HTR2A (0.46) | MEN1KMT2AHTR2CHTR1DLMNA | |
| SCHEMBL1828071 | 0.74 | TAAR1 (0.44) | HTR2CLMNAHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506212-A2 | NOVEL SUBSTITUTED SULFAMATE ANTICONVULSANT DERIVATIVES | Ortho-McNeil Pharmaceutical, Inc. (US) | 2005-02-16 | — | — | EP | claimed |
| WO-2003097656-A2 | NOVEL SUBSTITUTED SULFAMATE ANTICONVULSANT DERIVATIVES | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2003-11-27 | — | — | WO | claimed |