Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10145149 | 0.90 | NPC1 (0.47) | ALDH1A1LMNABRD4KDM4ESMN1; SMN2 | |
| SCHEMBL2685272 | 0.83 | BRD4 (0.48) | ALDH1A1BRD4TSHRKDM4EPOLB | |
| SCHEMBL11793288 | 0.81 | LMNA (0.60) | ALDH1A1LMNATSHRESR1CHRM1 | |
| SCHEMBL29909826 | 0.80 | BRD4 (0.50) | ALDH1A1BRD4TSHRTDP1POLB | |
| SCHEMBL1401093 | 0.80 | BRD4 (0.50) | ALDH1A1BRD4TSHRTDP1POLB | |
| SCHEMBL3012969 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRKDM4EPOLB | |
| SCHEMBL31239046 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNATSHRKDM4EPOLB | |
| SCHEMBL24449497 | 0.79 | BRD4 (0.49) | BRD4 | |
| SCHEMBL9647857 | 0.78 | BRD4 (0.51) | ALDH1A1LMNABRD4TSHRTDP1 | |
| SCHEMBL28336888 | 0.78 | KMT2A (0.52) | ALDH1A1LMNAKMT2ASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553929-A2 | CONTROLLED RELEASE PREPARATION | Takeda Pharmaceutical Company Limited (JP) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004035020-A2 | CONTROLLED RELEASE PREPARATION | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-04-29 | — | — | WO | disclosed |