Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 4/20 | 0.50 |
| ▸ | FNTB | P49356 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382326 | 0.91 | FNTA (0.54) | FNTAFNTBALDH1A1NPSR1PGGT1B | |
| SCHEMBL6381218 | 0.90 | FNTA (0.51) | FNTAFNTBALDH1A1NPSR1PGGT1B | |
| SCHEMBL6384342 | 0.83 | FNTA (0.59) | FNTAFNTBALDH1A1NPSR1 | |
| SCHEMBL6503160 | 0.81 | KMT2A (0.50) | FNTAFNTBALDH1A1TDP1 | |
| SCHEMBL6624891 | 0.81 | FNTA (0.66) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL6624887 | 0.81 | FNTA (0.66) | FNTAFNTBPGGT1BTDP1 | |
| SCHEMBL8623763 | 0.78 | FNTA (0.57) | FNTAFNTBALDH1A1NPSR1PGGT1B | |
| SCHEMBL2330623 | 0.78 | CA2 (0.55) | FNTAFNTBALDH1A1NPSR1PGGT1B | |
| SCHEMBL2330625 | 0.78 | CA2 (0.55) | FNTAFNTBALDH1A1NPSR1PGGT1B | |
| SCHEMBL8623007 | 0.77 | FNTA (0.67) | FNTAFNTBALDH1A1NPSR1PGGT1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209217-A1 | 3-Mercaptopyrrolidines as farnesyl protein transferase inhibitors | BOYLE FRANCIS T | 2005-09-22 | — | — | US | disclosed |
| EP-0923545-A1 | 3-MERCAPTOPYRROLIDINES AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998007692-A1 | 3-MERCAPTOPYRROLIDINES AS FARNESYL PROTEIN TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 1998-02-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209217-A1 | 3-Mercaptopyrrolidines as farnesyl protein transferase inhibitors | FNTB, FNTA, KRAS | FNTA 2/4885FNTB 1/4885ALDH1A1 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.