Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 6/20 | 0.49 |
| ▸ | FNTB | P49356 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381218 | 0.91 | FNTA (0.51) | FNTAFNTBTDP1TSHRALDH1A1 | |
| SCHEMBL629151 | 0.81 | FNTA (0.67) | KMT2AFNTAFNTBTDP1L3MBTL1 | |
| SCHEMBL6387223 | 0.81 | FNTA (0.50) | FNTAFNTBTDP1ALDH1A1 | |
| SCHEMBL629135 | 0.81 | FNTA (0.67) | KMT2AFNTAFNTBTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5935190 | 0.81 | FNTA (0.66) | KMT2AFNTAFNTBTDP1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL5935191 | 0.81 | FNTA (0.66) | KMT2AFNTAFNTBTDP1L3MBTL1 | |
| SCHEMBL6503164 | 0.78 | ITGB2 (0.39) | KMT2AFNTAFNTBALDH1A1 | |
| SCHEMBL6777600 | 0.77 | FNTA (0.62) | FNTAFNTBTDP1TAS1R3TAS1R1 | |
| SCHEMBL6777598 | 0.77 | FNTA (0.62) | FNTAFNTBTDP1TAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL6775701 | 0.76 | FNTA (0.61) | FNTAFNTBTDP1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6946468-B1 | 3-mercaptopyrrolidines as farnesyl protein transferase inhibitors | ZENECA LIMITED (GB) | 2005-09-20 | — | — | US | disclosed |