SCHEMBL6387948

SCHEMBL6387948

c1ccc(-c2ccc(-c3ccc4ccc5cccc6ccc3c4c56)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.47
ERBB2 P04626 1/20 0.47
FYN P06241 1/20 0.47
MAOA P21397 1/20 0.47
ACHE P22303 1/20 0.47
AHR P35869 1/20 0.47
ALDH1A1 P00352 8/20 0.46
HPGD P15428 6/20 0.46
HSD17B10 Q99714 5/20 0.46
THRB P10828 1/20 0.46
TSHR P16473 3/20 0.45
CYP3A4 P08684 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
CYP1A1 P04798 1/20 0.44
CYP1B1 Q16678 1/20 0.44
TNF P01375 1/20 0.42
HSD17B1 P14061 1/20 0.41
HSD17B2 P37059 1/20 0.41
PDE6D O43924 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29789609 0.96 ALDH1A1 (0.50) CYP1A2ERBB2FYNMAOAACHE
Benzene SCHEMBL27999683 0.96 ALDH1A1 (0.50) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL28840215 0.96 ALDH1A1 (0.50) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL359994 0.96 ALDH1A1 (0.50) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL29512003 0.92 ALDH1A1 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL29547734 0.92 ALDH1A1 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL2122937 0.92 ALDH1A1 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL18878313 0.91 CYP1A2 (0.41) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL18878307 0.91 CYP1A2 (0.41) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL18174838 0.90 CYP1A2 (0.40) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101080376-A Pyrene compound and light-emitting transistor element using same PIONEER CORP (JP) 2007-11-28 CN disclosed
US-20050238920-A1 1,3,6,8-Tetrasubstituted pyrene compound, organic electroluminescent element, and organic electroluminescent display FUJITSU LIMITED (JP) 2005-10-27 US disclosed