Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.55 |
| ▸ | OSBP | P22059 | 3/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.55 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.51 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.49 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6390172 | 1.00 | RORC (0.55) | RORCOSBPUSP2CYP46A1LMNA | |
| SCHEMBL6839053 | 0.92 | RORC (0.55) | RORCOSBPUSP2CYP46A1LMNA | |
| SCHEMBL6393980 | 0.92 | RORC (0.55) | RORCOSBPUSP2CYP46A1LMNA | |
| SCHEMBL27505687 | 0.89 | OSBP (0.69) | RORCOSBPUSP2CYP46A1LMNA | |
| SCHEMBL27505688 | 0.89 | OSBP (0.69) | RORCOSBPUSP2CYP46A1LMNA | |
| SCHEMBL27505694 | 0.86 | RORC (0.53) | RORCOSBPUSP2CYP46A1LMNA | |
| SCHEMBL27505693 | 0.86 | RORC (0.53) | RORCOSBPUSP2CYP46A1LMNA | |
| SCHEMBL6392365 | 0.86 | RORC (0.55) | RORCOSBPUSP2CYP46A1LMNA | |
| SCHEMBL6393216 | 0.86 | RORC (0.55) | RORCOSBPUSP2CYP46A1LMNA | |
| SCHEMBL6387282 | 0.85 | OSBP (0.70) | RORCOSBPUSP2CYP46A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004382-A1 | Meiosis regulating compounds | GRONDAHL CHRISTIAN (DK) | 2005-01-06 | — | — | US | disclosed |
| US-6759400-B2 | Meiosis regulating compounds | NOVO NORDISK A/S (DK) | 2004-07-06 | — | — | US | disclosed |
| EP-0946584-B1 | Meiosis regulating compounds | NOVO NORDISK AS (DK) | 2003-04-23 | — | — | EP | disclosed |
| US-20030032824-A1 | Meiosis regulating compounds | GRONDAHL CHRISTIAN (DK) | 2003-02-13 | — | — | US | disclosed |
| US-6486145-B2 | STEROL DERIVATIVE USEFUL IN TREATMENT OF FERTILITY | NOVO NORDISK A/S (DK) | 2002-11-26 | — | — | US | disclosed |
| US-20010005757-A1 | Meiosis regulating compounds | GRONDAHL CHRISTIAN (DK) | 2001-06-28 | — | — | US | disclosed |
| EP-0946584-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028323-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032824-A1 | Meiosis regulating compounds | MNS1, NR5A1, NASP | RORC 1053/4885OSBP 95/4885USP2 4505/4885 |
| US-20010005757-A1 | Meiosis regulating compounds | MNS1, NR5A1, NASP | RORC 1053/4885OSBP 95/4885USP2 4505/4885 |
| US-20050004382-A1 | Meiosis regulating compounds | NASP, MNS1, NR5A1 | RORC 687/4885OSBP 95/4885USP2 4426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.