Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 6/20 | 0.55 |
| ▸ | OSBP | P22059 | 4/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.55 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.51 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.49 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.48 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.48 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6393980 | 1.00 | RORC (0.55) | RORCOSBPUSP2CYP46A1OSBP2 | |
| SCHEMBL6390172 | 0.92 | RORC (0.55) | RORCOSBPUSP2CYP46A1OSBP2 | |
| SCHEMBL6388436 | 0.92 | RORC (0.55) | RORCOSBPUSP2CYP46A1OSBP2 | |
| SCHEMBL27505694 | 0.86 | RORC (0.53) | RORCOSBPUSP2CYP46A1OSBP2 | |
| SCHEMBL27505693 | 0.86 | RORC (0.53) | RORCOSBPUSP2CYP46A1OSBP2 | |
| SCHEMBL6387153 | 0.86 | RORC (0.55) | RORCOSBPUSP2CYP46A1OSBP2 | |
| SCHEMBL6388489 | 0.86 | RORC (0.55) | RORCOSBPUSP2CYP46A1OSBP2 | |
| SCHEMBL6388608 | 0.85 | OSBP (0.70) | RORCOSBPUSP2CYP46A1OSBP2 | |
| SCHEMBL6389574 | 0.85 | OSBP (0.70) | RORCOSBPUSP2CYP46A1OSBP2 | |
| SCHEMBL6392335 | 0.85 | OSBP (0.70) | RORCOSBPUSP2CYP46A1OSBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759400-B2 | Meiosis regulating compounds | NOVO NORDISK A/S (DK) | 2004-07-06 | — | — | US | disclosed |
| US-6486145-B2 | STEROL DERIVATIVE USEFUL IN TREATMENT OF FERTILITY | NOVO NORDISK A/S (DK) | 2002-11-26 | — | — | US | disclosed |