Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.56 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.52 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6389206 | 1.00 | NPY5R (0.56) | NPY5RCDK2CCNA2CCNA1KMT2A | |
| SCHEMBL6388838 | 0.93 | CCNA2 (0.55) | NPY5RCDK2CCNA2CCNA1KMT2A | |
| SCHEMBL6388842 | 0.93 | CCNA2 (0.55) | NPY5RCDK2CCNA2CCNA1KMT2A | |
| SCHEMBL6389857 | 0.91 | CCNA2 (0.52) | NPY5RCDK2CCNA2CCNA1KMT2A | |
| SCHEMBL6389855 | 0.91 | CCNA2 (0.52) | NPY5RCDK2CCNA2CCNA1KMT2A | |
| SCHEMBL6385331 | 0.89 | CCNA2 (0.49) | NPY5RCDK2CCNA2CCNA1KMT2A | |
| SCHEMBL6385334 | 0.89 | CCNA2 (0.49) | NPY5RCDK2CCNA2CCNA1KMT2A | |
| SCHEMBL6387001 | 0.86 | ALDH1A1 (0.53) | NPY5RCDK2CCNA2CCNA1KMT2A | |
| SCHEMBL6387004 | 0.86 | ALDH1A1 (0.53) | NPY5RCDK2CCNA2CCNA1KMT2A | |
| SCHEMBL5867539 | 0.86 | CCNA2 (0.66) | NPY5RCDK2CCNA2CCNA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050209297-A1 | Pyrazole derivatives | PFIZER INC | 2005-09-22 | — | — | US | claimed |
| US-20020103185-A1 | Pyrazole derivatives | PFIZER PRODUCTS INC. | 2002-08-01 | — | — | US | claimed |
| US-20050209297-A1 | Pyrazole derivatives | PFIZER INC | 2005-09-22 | — | — | US | disclosed |
| US-20020103185-A1 | Pyrazole derivatives | PFIZER PRODUCTS INC. | 2002-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209297-A1 | Pyrazole derivatives | CDK1, CDK3, CDK5 | NPY5R 2899/4885CDK2 7/4885CCNA2 482/4885 |
| US-20020103185-A1 | Pyrazole derivatives | CDK1, CDK5, CDK3 | NPY5R 2776/4885CDK2 5/4885CCNA2 558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.