Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25840308 | 0.83 | KCNN4 (0.44) | PTPN1ALDH1A1TSHRKCNN4RAB9A | |
| SCHEMBL10825012 | 0.76 | KCNN4 (0.48) | PTPN1ALDH1A1TSHRKCNN4MAPT | |
| SCHEMBL9159682 | 0.76 | KCNN4 (0.45) | PTPN1ALDH1A1TSHRKCNN4MAPT | |
| SCHEMBL8795628 | 0.75 | HDAC3 (0.44) | PTPN1ALDH1A1TSHRKCNN4RAB9A | |
| Hydrochloric Acid SCHEMBL11410463 | 0.74 | KCNN4 (0.43) | PTPN1ALDH1A1TSHRKCNN4MAPT | |
| SCHEMBL22494164 | 0.74 | ALDH1A1 (0.41) | PTPN1ALDH1A1TSHRKCNN4MAPT | |
| SCHEMBL22200647 | 0.73 | TSHR (0.50) | PTPN1ALDH1A1TSHRKCNN4RAB9A | |
| SCHEMBL935057 | 0.73 | SSTR4 (0.53) | KCNN4MAPTKMT2ACYP1A2HDAC3 | |
| SCHEMBL28905042 | 0.73 | HDAC3 (0.50) | ALDH1A1KCNN4MAPTKMT2ACYP1A2 | |
| SCHEMBL17202376 | 0.73 | KCNN4 (0.42) | PTPN1TSHRKCNN4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |