Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11410463 | 0.98 | KCNN4 (0.43) | KCNN4CYP1A2HDAC3HDAC4HDAC1 | |
| SCHEMBL28905040 | 0.86 | KCNN4 (0.48) | KCNN4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28397741 | 0.82 | KDM4E (0.50) | KMT2AMAPTSMN1; SMN2MEN1TSHR | |
| SCHEMBL31358110 | 0.81 | KCNN4 (0.47) | KCNN4CYP1A2HDAC3HDAC4HDAC1 | |
| SCHEMBL11410462 | 0.81 | CYP1A2 (0.46) | KCNN4CYP1A2HDAC3HDAC4HDAC1 | |
| SCHEMBL10825012 | 0.80 | KCNN4 (0.48) | KCNN4CYP1A2HDAC3HDAC4HDAC1 | |
| SCHEMBL29897719 | 0.78 | LMNA (0.46) | KCNN4CYP1A2KMT2AMAPTCYP2C19 | |
| SCHEMBL11021343 | 0.78 | KCNN4 (0.53) | KCNN4CYP1A2HDAC3HDAC4HDAC1 | |
| SCHEMBL6392143 | 0.76 | PTPN1 (0.45) | KCNN4CYP1A2HDAC3HDAC4HDAC1 | |
| SCHEMBL28905042 | 0.76 | HDAC3 (0.50) | KCNN4CYP1A2HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110732-B1 | PROCESS FOR PRODUCING DIPHENYLMETHANE DICARBAMATES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1987-03-11 | — | — | EP | claimed |
| EP-0123412-B1 | METHOD FOR MANUFACTURE OF DIPHENYLMETHANE DIISOCYANATES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1986-07-09 | — | — | EP | claimed |
| EP-0016441-B1 | A METHOD FOR THE PREPARATION OF A MIXTURE OF DIPHENYL METHANE DICARBAMATES AND POLYMETHYLENE POLYPHENYL CARBAMATES | ATLANTIC RICHFIELD COMPANY (US) | 1982-05-12 | — | — | EP | claimed |
| EP-0014482-B1 | PREPARATION OF DIPHENYLMETHANE DICARBAMATES AND POLYMETHYLENE POLYPHENYL CARBAMATES WITH LEWIS ACID CATALYSTS INTERCALATED IN GRAPHITE | ATLANTIC RICHFIELD COMPANY (US) | 1981-11-25 | — | — | EP | claimed |
| EP-0410900-B1 | Method for the preparation of methylene di(phenylurethane) | RHONE POULENC CHIMIE (FR) | 1995-03-15 | — | — | EP | disclosed |
| EP-0406129-B1 | Method for the preparation of methylene di(phenylurethane) | RHONE POULENC CHIMIE (FR) | 1994-11-23 | — | — | EP | disclosed |
| EP-0410900-A1 | Method for the preparation of methylene di(phenylurethane) | RHONE-POULENC CHIMIE (FR) | 1991-01-30 | — | — | EP | disclosed |
| EP-0406129-A1 | Method for the preparation of methylene di(phenylurethane) | RHONE-POULENC CHIMIE (FR) | 1991-01-02 | — | — | EP | disclosed |
| EP-0041613-B1 | DERIVATIVES OF ARALKYLANILINE AND HERBICIDES CONTAINING THESE COMPOUNDS | BASF Aktiengesellschaft (DE) | 1984-02-01 | — | — | EP | disclosed |