Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | EEF2K | O00418 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CTSA | P10619 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25375819 | 0.79 | GAA (0.50) | GAACNR2CES2CES1MEN1 | |
| SCHEMBL27228952 | 0.77 | CNR2 (0.50) | GAACNR2CES2CES1EEF2K | |
| SCHEMBL6398252 | 0.75 | CYP2D6 (0.44) | CES2CES1KMT2ALMNAHDAC4 | |
| SCHEMBL15269542 | 0.75 | ROCK2 (0.47) | GAACNR2CES2CES1MEN1 | |
| SCHEMBL16054881 | 0.75 | GAA (0.46) | GAACNR2CES2CES1MEN1 | |
| SCHEMBL3447746 | 0.74 | CNR2 (0.48) | GAACNR2CES2CES1EEF2K | |
| SCHEMBL19458984 | 0.74 | CNR2 (0.50) | GAACNR2CES2CES1MEN1 | |
| Hydrochloric Acid SCHEMBL22190205 | 0.74 | IDO1 (0.40) | GAACNR2CES2CES1MEN1 | |
| SCHEMBL28041534 | 0.72 | MEN1 (0.45) | GAACNR2CES2CES1MEN1 | |
| SCHEMBL27992149 | 0.72 | CNR2 (0.46) | GAACNR2CES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |