SCHEMBL27992149

SCHEMBL27992149

CCC(O)C(NC(=O)O)c1ccccc1F

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.46
GAA P10253 1/20 0.43
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
HIF1A Q16665 1/20 0.39
CTSA P10619 2/20 0.38
KCNQ2 O43526 1/20 0.38
TAS1R3 Q7RTX0 1/20 0.38
TAS1R1 Q7RTX1 1/20 0.38
CYP3A4 P08684 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
LMNA P02545 3/20 0.36
ALDH1A1 P00352 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
POLB P06746 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27992292 0.83 TRPA1 (0.37) GAAMEN1KMT2ACYP3A4LMNA
SCHEMBL16054881 0.83 GAA (0.46) CNR2GAACES2CES1MEN1
SCHEMBL27992133 0.82 CASP1 (0.46) GAAHIF1ACTSAKCNQ2TAS1R3
SCHEMBL28990587 0.81 GAA (0.43) CNR2GAAMEN1KMT2AHIF1A
SCHEMBL28041751 0.77 GAA (0.40) CNR2GAAMEN1KMT2AHIF1A
SCHEMBL28041534 0.76 MEN1 (0.45) CNR2GAACES2CES1MEN1
SCHEMBL25375819 0.74 GAA (0.50) CNR2GAACES2CES1MEN1
SCHEMBL28041588 0.73 CNR2 (0.41) CNR2GAAMEN1KMT2AHIF1A
SCHEMBL6392149 0.72 GAA (0.51) CNR2GAACES2CES1MEN1
SCHEMBL5682350 0.72 CYP3A4 (0.44) CNR2CES2CES1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111419830-B Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epileptic related syndromes 比皮艾思药物研发有限公司 2024-01-30 CN disclosed
CN-115996905-A Phenylalkyl carbamate compounds for use in preventing or treating neurodegenerative diseases 生物药品解决方案有限公司 2023-04-21 CN disclosed
CN-104136416-B Phenylalkylamino carbamate derivatives compound and comprise the pharmaceutical composition of this Phenylalkylamino carbamate derivatives compound 比皮艾思药物研发有限公司 2016-11-09 CN disclosed
CN-105209027-A Phenylalkylcarbamate compounds for use in the prevention or treatment of epilepsy and epilepsy-related syndromes BIO PHARM SOLUTIONS CO LTD 2015-12-30 CN disclosed
CN-104136416-A Phenyl alkyl carbamate derivative compound and pharmaceutical composition containing the same BIO PHARM SOLUTIONS CO LTD 2014-11-05 CN disclosed