Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28017337 | 0.77 | ALOX5 (0.53) | SRCCYP2D6LMNAMAPK1ALOX5 | |
| SCHEMBL2525081 | 0.74 | DPP4 (0.39) | SRCCYP2D6TDP1 | |
| SCHEMBL11707792 | 0.72 | DPP4 (0.38) | SRCCYP2D6TDP1 | |
| SCHEMBL14694051 | 0.71 | CYP2D6 (0.40) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL11097148 | 0.71 | MEN1 (0.45) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL241909 | 0.67 | SRC (0.56) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL28232530 | 0.67 | SRC (0.56) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL9394507 | 0.67 | SRC (0.50) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL28232476 | 0.67 | SRC (0.56) | SRCCYP2D6LMNAMAPK1CES2 | |
| SCHEMBL16114585 | 0.67 | KDM4E (0.46) | TDP1ALOX5KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |