Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6267290 | 1.00 | HCAR2 (0.59) | HCAR2ALDH1A1CYP3A4HSD17B10TP53 | |
| SCHEMBL114793 | 1.00 | HCAR2 (0.59) | HCAR2ALDH1A1CYP3A4HSD17B10TP53 | |
| SCHEMBL2292807 | 1.00 | HCAR2 (0.59) | HCAR2ALDH1A1CYP3A4HSD17B10TP53 | |
| Hydrochloric Acid SCHEMBL27545522 | 0.98 | HCAR2 (0.58) | HCAR2ALDH1A1CYP3A4HSD17B10TP53 | |
| Ethylene Glycol SCHEMBL2515273 | 0.92 | HCAR2 (0.53) | HCAR2ALDH1A1CYP3A4HSD17B10TP53 | |
| Alcohol SCHEMBL4648871 | 0.92 | HCAR2 (0.53) | HCAR2ALDH1A1CYP3A4HSD17B10TP53 | |
| Phenyl Ethanol SCHEMBL28893774 | 0.92 | HCAR2 (0.53) | HCAR2ALDH1A1CYP3A4HSD17B10TP53 | |
| Propionic Acid SCHEMBL15377928 | 0.91 | HCAR2 (0.51) | HCAR2ALDH1A1CYP3A4HSD17B10TP53 | |
| SCHEMBL10521081 | 0.88 | PTGS2 (0.56) | HCAR2ALDH1A1CYP3A4MMP12 | |
| SCHEMBL9328620 | 0.88 | PDCD1 (0.51) | HCAR2ALDH1A1CYP3A4HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124646-A1 | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124646-A1 | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same | OTC, OAT, SLC11A2 | HCAR2 1321/4885ALDH1A1 2863/4885CYP3A4 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.