Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6388251 | 0.91 | CNR2 (0.43) | TDP1CNR2CNR1MAPTGAA | |
| SCHEMBL6386892 | 0.83 | TDP1 (0.43) | TDP1CNR2CNR1NR1H4LMNA | |
| SCHEMBL529153 | 0.83 | TDP1 (0.40) | TDP1CNR2CNR1MAPTGAA | |
| SCHEMBL6388805 | 0.82 | TDP1 (0.44) | TDP1CNR2CNR1NR1H4LMNA | |
| SCHEMBL18039231 | 0.81 | TDP1 (0.40) | TDP1CNR2CNR1MAPTNR1H4 | |
| SCHEMBL6386762 | 0.75 | LMNA (0.41) | TDP1CNR2CNR1MAPTLMNA | |
| SCHEMBL7250262 | 0.74 | TDP1 (0.48) | TDP1LMNASMN1; SMN2ALDH1A1ACHE | |
| SCHEMBL527982 | 0.73 | TDP1 (0.42) | TDP1CNR2CNR1NR1H4LMNA | |
| SCHEMBL528739 | 0.73 | LMNA (0.44) | CNR2CNR1LMNASMN1; SMN2ACHE | |
| SCHEMBL6388980 | 0.72 | TDP1 (0.46) | TDP1LMNASMN1; SMN2ALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603553-A2 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | JAPAN TOBACCO INC. (JP) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004082593-A2 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | JAPAN TOBACCO INC. (JP) | 2004-09-30 | — | — | WO | disclosed |