Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 3/20 | 0.79 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.60 |
| ▸ | OSBP | P22059 | 5/20 | 0.59 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.59 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.58 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.58 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.58 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6393174 | 1.00 | RORC (0.79) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| SCHEMBL6386385 | 1.00 | RORC (0.79) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| SCHEMBL8473345 | 1.00 | RORC (0.79) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| SCHEMBL6389582 | 1.00 | RORC (0.79) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL23565992 | 0.89 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL288290 | 0.89 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL12917612 | 0.89 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL13833045 | 0.89 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL2154711 | 0.89 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP | |
| Desmosterol SCHEMBL288990 | 0.89 | RORC (1.00) | RORCGRIN1GRIN2AGRIN2BOSBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004382-A1 | Meiosis regulating compounds | GRONDAHL CHRISTIAN (DK) | 2005-01-06 | — | — | US | disclosed |
| EP-0946584-B1 | Meiosis regulating compounds | NOVO NORDISK AS (DK) | 2003-04-23 | — | — | EP | disclosed |
| EP-0946584-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028323-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1998-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004382-A1 | Meiosis regulating compounds | NASP, MNS1, NR5A1 | RORC 687/4885GRIN1 4613/4885GRIN2A 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.