Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6398310 | 0.86 | CRHR1 (0.72) | CRHR1 | |
| SCHEMBL5845505 | 0.85 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL6799632 | 0.83 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL29482253 | 0.82 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL3226278 | 0.82 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL5844210 | 0.80 | CRHR1 (0.73) | CRHR1 | |
| SCHEMBL8202430 | 0.80 | CRHR1 (0.84) | CRHR1 | |
| SCHEMBL5843964 | 0.79 | CRHR1 (0.46) | CRHR1 | |
| SCHEMBL5843305 | 0.77 | CRHR1 (0.76) | CRHR1 | |
| SCHEMBL5844212 | 0.77 | CRHR1 (0.76) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6956047-B1 | Corticotropin releasing factor antagonists | PFIZER INC. (US) | 2005-10-18 | — | — | US | disclosed |