Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17141355 | 0.81 | ATM (0.39) | SMN1; SMN2PKMALDH1A1TSHRCYP2C19 | |
| SCHEMBL17141389 | 0.81 | ATM (0.39) | SMN1; SMN2PKMALDH1A1TSHRCYP2C19 | |
| SCHEMBL2697887 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMALDH1A1TSHRMAPT | |
| SCHEMBL6628443 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2PKMALDH1A1TSHRCYP3A4 | |
| SCHEMBL1070950 | 0.78 | SMN1; SMN2 (0.42) | SMN1; SMN2PKMALDH1A1TSHRCYP3A4 | |
| SCHEMBL1070614 | 0.78 | TSHR (0.47) | SMN1; SMN2PKMALDH1A1TSHRMAPT | |
| SCHEMBL8939923 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2PKMALDH1A1TSHRCYP3A4 | |
| SCHEMBL23037020 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2PKMALDH1A1TSHRCYP3A4 | |
| SCHEMBL6632269 | 0.76 | CHRM5 (0.44) | KMT2A | |
| SCHEMBL5845946 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2PKMALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |