Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615098 | 0.81 | TGFBR1 (0.37) | TGFBR1ALDH1A1KMT2ATSHRKDM4E | |
| SCHEMBL8065835 | 0.80 | ALDH1A1 (0.40) | SMN1; SMN2PKMTGFBR1ALDH1A1LMNA | |
| SCHEMBL733022 | 0.79 | CHRM5 (0.40) | TGFBR1 | |
| SCHEMBL6396274 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMALDH1A1LMNAMAPT | |
| SCHEMBL9807354 | 0.77 | ALDH1A1 (0.36) | TGFBR1ALDH1A1TSHRCYP3A4CYP2C19 | |
| SCHEMBL1070614 | 0.76 | TSHR (0.47) | SMN1; SMN2PKMALDH1A1LMNAMAPT | |
| SCHEMBL6628443 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2PKMALDH1A1LMNAMAPT | |
| SCHEMBL2697887 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMALDH1A1LMNAMAPT | |
| SCHEMBL14166869 | 0.72 | ALDH1A1 (0.52) | SMN1; SMN2PKMALDH1A1LMNAMAPT | |
| SCHEMBL1147606 | 0.71 | CYP2D6 (0.45) | SMN1; SMN2KMT2ARAB9APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10551345-B2 | Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis | APPLIED BIOSYSTEMS, LLC (US) | 2020-02-04 | — | — | US | claimed |
| US-20170356877-A1 | POLY AND COPOLY(N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS | APPLIED BIOSYSTEMS, LLC (US) | 2017-12-14 | — | — | US | claimed |
| US-9671367-B2 | Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis | APPLIED BIOSYSTEMS, LLC (US) | 2017-06-06 | — | — | US | claimed |
| US-20150159009-A1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | APPLIED BIOSYSTEMS LLC (US) | 2015-06-11 | — | — | US | claimed |
| US-20140209461-A1 | Poly and Copoly(N-vinylamide)s and Their Use In Capillary Electrophoresis | APPLIED BIOSYSTEMS, LLC (US) | 2014-07-31 | — | — | US | claimed |
| US-20130153421-A1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | APPLIED BIOSYSTEMS, LLC (US) | 2013-06-20 | — | — | US | claimed |
| EP-2053067-B1 | Poly and copoly (N-vinylamide)s and their use in capillary electrophoresis | APPLIED BIOSYSTEMS LLC (US) | 2011-09-14 | — | — | EP | claimed |
| EP-2275463-A1 | Support for electrophoresis containing a composition and method | Life Technologies Corporation (US) | 2011-01-19 | — | — | EP | claimed |
| EP-1539846-B1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | LIFE TECHNOLOGIES CORP (US) | 2010-09-08 | — | — | EP | claimed |
| US-20100051461-A1 | Poly and Copolyn(N-Vinylamide)s and their use in Capillary Electrophoresis | Life Technologies Corporation (US) | 2010-03-04 | — | — | US | claimed |
| EP-2053067-A1 | Poly and copoly (N-vinylamide)s and their use in capillary electrophoresis | Applied Biosystems Inc. (US) | 2009-04-29 | — | — | EP | claimed |
| EP-1636279-B1 | POLY AND COPOLY (N -VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS | APPLIED BIOSYSTEMS (US) | 2009-02-18 | — | — | EP | claimed |
| EP-1636279-A1 | POLY AND COPOLY (N -VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS | Applera Corporation (US) | 2006-03-22 | — | — | EP | claimed |
| US-20050234166-A1 | Graft copolymers, their preparation and use in capillary electrophoresis | APPLIED BIOSYSTEMS, INC. | 2005-10-20 | — | — | US | claimed |
| EP-1539846-A1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | Applera Corporation (US) | 2005-06-15 | — | — | EP | claimed |
| US-20050025741-A1 | Copolymers with (meth)acrylamides; improved separation of polynucleotides | APPLIED BIOSYSTEMS, LLC | 2005-02-03 | — | — | US | claimed |
| WO-2004104054-A1 | POLY AND COPOLY (N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS | APPLERA CORPORATION (US) | 2004-12-02 | — | — | WO | claimed |
| WO-2004011513-A1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | APPLERA CORPORATION (US) | 2004-02-05 | — | — | WO | claimed |
| US-10551345-B2 | Poly and copoly(N-vinylamide)s and their use in capillary electrophoresis | APPLIED BIOSYSTEMS, LLC (US) | 2020-02-04 | — | — | US | disclosed |
| WO-2004011513-A1 | GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS | APPLERA CORPORATION (US) | 2004-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050025741-A1 | Copolymers with (meth)acrylamides; improved separation of polynucleotides | POLI, PCNA, POLL | SMN1; SMN2 963/4885PKM 1372/4885TGFBR1 4144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.