SCHEMBL6397365

SCHEMBL6397365

C=C(F)C(F)(F)S(=O)(=O)F

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6536998 0.79 ALDH1A1 (0.33) ALDH1A1L3MBTL1
SCHEMBL3257814 0.77 ALDH1A1 (0.50) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL4102252 0.75 TSHR (0.35) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL1054681 0.73 ALDH1A1 (0.39) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL16990129 0.72 CA1 (0.36)
SCHEMBL27771794 0.71 ALDH1A1 (0.32) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL22072254 0.69 ALDH1A1 (0.41) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL10020904 0.67
SCHEMBL28373 0.67 ALDH1A1 (0.60) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL3434802 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030162787-A1 Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade WARNER-LAMBERT COMPANY LLC 2003-08-28 US claimed
US-20050250815-A1 Inhibitors of fractor Xa and other serine proteases involved in the coagulation cascade WARNER-LAMBERT COMPANY LLC 2005-11-10 US disclosed
US-6890855-B2 Process of removing residue material from a precision surface INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2005-05-10 US disclosed
US-20030162787-A1 Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade WARNER-LAMBERT COMPANY LLC 2003-08-28 US disclosed
US-20030003762-A1 Process of removing residue material from a precision surface INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2003-01-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162787-A1 Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade TFPI, F11, F12 ALDH1A1 2068/4885L3MBTL1 2331/4885TSHR 3185/4885
US-20050250815-A1 Inhibitors of fractor Xa and other serine proteases involved in the coagulation cascade F12, TFPI, F11 ALDH1A1 3666/4885L3MBTL1 2166/4885TSHR 2034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.