Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17754467 | 1.00 | CHRNA7 (0.36) | CHRNA7SLC6A2SLC6A3TAAR1MAPK1 | |
| SCHEMBL17747362 | 0.79 | ALDH1A1 (0.34) | LMNAALDH1A1ALOX12SMN1; SMN2HTR2A | |
| SCHEMBL7100928 | 0.79 | ATM (0.39) | SLC6A2SLC6A3SLC6A4HTR2AHTR2C | |
| SCHEMBL17747364 | 0.79 | ALDH1A1 (0.34) | LMNAALDH1A1ALOX12SMN1; SMN2HTR2A | |
| SCHEMBL17754471 | 0.79 | ATM (0.39) | SLC6A2SLC6A3SLC6A4HTR2AHTR2C | |
| SCHEMBL17754470 | 0.78 | TSHR (0.44) | SLC6A2SLC6A3TAAR1LMNACYP2A6 | |
| SCHEMBL17747348 | 0.76 | ALDH1A1 (0.41) | CYP2A6ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL17747346 | 0.76 | ALDH1A1 (0.41) | CYP2A6ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL17754466 | 0.75 | MAOA (0.43) | SLC6A2SLC6A3MAPK1SLC6A4ALDH1A1 | |
| SCHEMBL16402611 | 0.75 | SLC6A2 (0.38) | SLC6A2SLC6A3LMNASLC6A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050192286-A1 | Ligands of melanocortin receptors and compositions and methods related thereto | NEUROCRINE BIOSCIENCES, INC. (US) | 2005-09-01 | — | — | US | disclosed |
| WO-2005040109-A1 | LIGANDS OF MELANOCORTIN RECEPTORS AND COMPOSITIONS AND METHODS RELATED THERETO | NEUROCRINE BIOSCIENCES, INC. (US) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050192286-A1 | Ligands of melanocortin receptors and compositions and methods related thereto | MC3R, MC1R, MC5R | CHRNA7 154/4885SLC6A2 312/4885SLC6A3 255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.