Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | CDYL2 | Q8N8U2 | 5/20 | 0.48 |
| ▸ | CDYL | Q9Y232 | 5/20 | 0.48 |
| ▸ | CBX7 | O95931 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399169 | 1.00 | KMT2A (0.57) | KMT2AMEN1RECQLNPC1RAB9A | |
| SCHEMBL5722008 | 0.93 | MEN1 (0.64) | KMT2AMEN1RECQLNPC1RAB9A | |
| SCHEMBL5722005 | 0.90 | MEN1 (0.69) | KMT2AMEN1RECQLNPC1RAB9A | |
| SCHEMBL5722010 | 0.90 | KMT2A (0.55) | KMT2AMEN1RECQLNPC1RAB9A | |
| SCHEMBL6403282 | 0.88 | MEN1 (0.58) | KMT2AMEN1RECQLNPC1RAB9A | |
| SCHEMBL6401164 | 0.87 | KMT2A (0.76) | KMT2AMEN1RECQLNPC1RAB9A | |
| SCHEMBL6401168 | 0.87 | KMT2A (0.76) | KMT2AMEN1RECQLNPC1RAB9A | |
| SCHEMBL6399497 | 0.85 | MEN1 (0.55) | KMT2AMEN1RECQLNPC1RAB9A | |
| Bromide SCHEMBL6010196 | 0.85 | MEN1 (0.56) | KMT2AMEN1RECQLNPC1RAB9A | |
| Bromide SCHEMBL6074278 | 0.85 | MEN1 (0.56) | KMT2AMEN1RECQLNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | SMITHKLINE BEECHAM CORPORATION | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | CXCR3, CXCR1, CCR7 | KMT2A 4040/4885MEN1 3721/4885RECQL 1290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.