Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.76 |
| ▸ | MEN1 | O00255 | 7/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401168 | 1.00 | KMT2A (0.76) | KMT2AMEN1RECQLMAPTLMNA | |
| SCHEMBL5722005 | 0.96 | MEN1 (0.69) | KMT2AMEN1RECQLMAPTLMNA | |
| SCHEMBL6399978 | 0.91 | MEN1 (0.62) | KMT2AMEN1RECQLMAPTGRIN2B | |
| SCHEMBL6398727 | 0.91 | MEN1 (0.62) | KMT2AMEN1RECQLMAPTGRIN2B | |
| SCHEMBL5721990 | 0.90 | KMT2A (0.60) | KMT2AMEN1RECQLMAPTLMNA | |
| SCHEMBL6404555 | 0.88 | MEN1 (0.58) | KMT2AMEN1RECQLMAPTLMNA | |
| SCHEMBL5722011 | 0.88 | MEN1 (0.58) | KMT2AMEN1RECQLMAPTLMNA | |
| Bromide SCHEMBL6074358 | 0.87 | KMT2A (1.00) | KMT2AMEN1RECQLMAPTLMNA | |
| SCHEMBL6399164 | 0.87 | KMT2A (0.57) | KMT2AMEN1RECQLMAPTALDH1A1 | |
| SCHEMBL6399169 | 0.87 | KMT2A (0.57) | KMT2AMEN1RECQLMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | SMITHKLINE BEECHAM CORPORATION | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272936-A1 | Imidazolium cxcr3 inhibitors | CXCR3, CXCR1, CCR7 | KMT2A 4040/4885MEN1 3721/4885RECQL 1290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.