Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399311 | 1.00 | CCR2 (0.49) | CCR2OPRD1NPSR1SPHK2SPHK1 | |
| SCHEMBL6399159 | 1.00 | CCR2 (0.49) | CCR2OPRD1NPSR1SPHK2SPHK1 | |
| SCHEMBL6398891 | 0.96 | OPRD1 (0.52) | CCR2OPRD1NPSR1SPHK2SPHK1 | |
| SCHEMBL3689270 | 0.77 | OPRD1 (0.53) | CCR2OPRD1SPHK2SPHK1 | |
| SCHEMBL14822485 | 0.77 | OPRD1 (0.53) | CCR2OPRD1SPHK2SPHK1 | |
| SCHEMBL312540 | 0.75 | SPHK1 (0.69) | SPHK2SPHK1 | |
| SCHEMBL2169692 | 0.75 | SPHK1 (0.69) | SPHK2SPHK1 | |
| SCHEMBL16050034 | 0.75 | SPHK2 (0.51) | OPRD1SPHK2SPHK1 | |
| SCHEMBL4926619 | 0.75 | SPHK1 (0.69) | SPHK2SPHK1 | |
| Acetic Acid SCHEMBL7451806 | 0.75 | SPHK1 (0.62) | OPRD1SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-0757051-B1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | DAIICHI SUNTORY PHARMA CO LTD (JP) | 2003-10-29 | — | — | EP | disclosed |
| EP-0757051-A1 | PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004092-A1 | Penem derivatives and antimicrobial agent containing the same | MRPL21, MRPS2, MRPS28 | CCR2 4367/4885OPRD1 3035/4885NPSR1 2443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.