SCHEMBL6399187

SCHEMBL6399187

Nc1ccc(-c2nc3c(N)cccc3o2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 14/20 0.60
RAB9A P51151 13/20 0.60
MEN1 O00255 6/20 0.60
KMT2A Q03164 6/20 0.60
ATM Q13315 2/20 0.60
ALDH1A1 P00352 8/20 0.51
KDM4E B2RXH2 7/20 0.51
MAPT P10636 7/20 0.51
SMN1; SMN2 Q16637 7/20 0.51
HPGD P15428 6/20 0.51
GLA P06280 3/20 0.51
GAA P10253 2/20 0.51
GFER P55789 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
HSD17B10 Q99714 6/20 0.44
TP53 P04637 5/20 0.44
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
NFKB1 P19838 2/20 0.43
NFKB2 Q00653 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10825753 0.95 NPC1 (0.51) NPC1RAB9AMEN1KMT2AATM
SCHEMBL31433078 0.88 RAB9A (0.53) NPC1RAB9AMEN1KMT2AATM
SCHEMBL7109574 0.88 RAB9A (0.53) NPC1RAB9AMEN1KMT2AATM
SCHEMBL4147435 0.87 RAB9A (0.46) NPC1RAB9AMEN1KMT2AATM
SCHEMBL2249487 0.87 NPC1 (0.51) NPC1RAB9AMEN1KMT2AATM
SCHEMBL24454935 0.83 NPC1 (0.57) NPC1RAB9AMEN1KMT2AATM
SCHEMBL30597434 0.83 NPC1 (0.60) NPC1RAB9AMEN1KMT2AATM
SCHEMBL6404572 0.83 NPC1 (0.60) NPC1RAB9AMEN1KMT2AATM
SCHEMBL1921033 0.83 NPC1 (0.57) NPC1RAB9AMEN1KMT2AATM
SCHEMBL18935916 0.83 IKBKB (0.48) NPC1RAB9AMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0826294-A1 PRINTED WIRING BOARD(S) HAVING POLYIMIDEBENZOXAZOLE DIELECTRIC LAYER(S) AND THE MANUFACTURE THEREOF THE DOW CHEMICAL COMPANY (US) 1998-03-04 EP claimed
WO-1996036204-A1 PRINTED WIRING BOARD(S) HAVING POLYIMIDEBENZOXAZOLE DIELECTRIC LAYER(S) AND THE MANUFACTURE THEREOF THE DOW CHEMICAL COMPANY (US) 1996-11-14 WO claimed
CN-108602792-B Tetracarboxylic dianhydride, polyamic acid, and polyimide 田冈化学工业株式会社 2021-12-17 CN disclosed
CN-107614495-A Tetracarboxylic dianhydride, polyamic acid, and polyimide having cyclic hydrocarbon skeleton and ester group 田冈化学工业株式会社 2018-01-19 CN disclosed
CN-104742461-B Low-gloss two-layer polyimide film and method for producing same 达迈科技股份有限公司 2017-05-24 CN disclosed
US-20050170077-A1 Adhesion method SHIPLEY COMPANY, L.L.C. (US) 2005-08-04 US disclosed
US-20040161545-A1 Adhesion method SHIPLEY COMPANY, L.L.C. 2004-08-19 US disclosed
US-5571891-A FROM 2-AMINOPHENYL-SUBSTITUTED AMINOBENZIMIDAZOLES, AMINOBENZOTHIAZOLES OR AMINOBENZOXAZOLES HOECHST AKTIENGESELLSCHAFT (DE) 1996-11-05 US disclosed
US-5004627-A Polyimides for mold release ETHYL CORPORATION (US) 1991-04-02 US disclosed
EP-0192937-B1 FLEXIBLE POLYIMIDE MULTILAYER LAMINATE Akzo Patente GmbH (DE) 1990-10-24 EP disclosed
EP-0249744-B1 PROCESS FOR MAKING POLYIMIDE-METAL LAMINATES AKZO N.V. (NL) 1989-10-11 EP disclosed
US-4705720-A FOR PRINTED CIRCUITS AKZO NV (NL) 1987-11-10 US disclosed
US-4699841-A PRINTED CIRCUITS AKZO NV (NL) 1987-10-13 US disclosed
US-4675246-A DIRECT BONDING WITH SUBSTRATE AND POLYIMIDE AKZO NV (NL) 1987-06-23 US disclosed
EP-0194413-A2 Printed circuit element with a cover sheet containing polyimide Akzo Patente GmbH (DE) 1986-09-17 EP disclosed
EP-0192937-A2 Flexible polyimide multilayer laminate Akzo Patente GmbH (DE) 1986-09-03 EP disclosed
EP-0167020-A2 Flexible polyimide multilayer laminate Akzo Patente GmbH (DE) 1986-01-08 EP disclosed
US-4522880-A EXTRUSION ON SUBSTRATE, THEN CURING AKZONA INCORPORATED (US) 1985-06-11 US disclosed
EP-0116297-A2 Polyimide laminate with peel-resistance and method of manufacturing it Akzo GmbH (DE) 1984-08-22 EP disclosed
US-4018735-A Anisotropic dopes of aromatic polyamides TEIJIN LIMITED (JA) 1977-04-19 US disclosed