Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | LDHB | P07195 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7152622 | 1.00 | PTGS2 (0.41) | PTGS2KDM4ETPMTTDP1NPSR1 | |
| SCHEMBL7146446 | 1.00 | PTGS2 (0.41) | PTGS2KDM4ETPMTTDP1NPSR1 | |
| SCHEMBL27635075 | 0.84 | CYP3A4 (0.45) | PTGS2TDP1HPGDAKR1C3AKR1C2 | |
| SCHEMBL28809532 | 0.80 | KDM4E (0.39) | KDM4ETPMTNPSR1HPGDMCOLN3 | |
| SCHEMBL6806673 | 0.79 | KDM4E (0.42) | KDM4ETPMTTDP1NPSR1HPGD | |
| SCHEMBL21269629 | 0.77 | KDM4E (0.41) | PTGS2KDM4ETPMTTDP1NPSR1 | |
| SCHEMBL21269842 | 0.77 | KDM4E (0.41) | KDM4ETPMTTDP1NPSR1HPGD | |
| SCHEMBL21268965 | 0.77 | KDM4E (0.41) | KDM4ETPMTTDP1NPSR1HPGD | |
| SCHEMBL29030339 | 0.77 | KDM4E (0.41) | KDM4ETPMTTDP1NPSR1HPGD | |
| SCHEMBL28799205 | 0.77 | KDM4E (0.41) | KDM4ETPMTTDP1NPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114106057-B | Synthesis and characterization of Ru alkylene complexes | 优美科股份公司及两合公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-3508489-B1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH ZUERICH (CH) | 2021-04-14 | — | — | EP | disclosed |
| EP-3508489-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH Zürich (CH) | 2019-07-10 | — | — | EP | disclosed |
| US-10273258-B2 | Process for the preparation of acylphosphanes | ETH ZUERICH (CH) | 2019-04-30 | — | — | US | disclosed |
| EP-2903995-B1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH ZUERICH (CH) | 2019-01-16 | — | — | EP | disclosed |
| US-20180002357-A1 | PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH ZUERICH (CH) | 2018-01-04 | — | — | US | disclosed |
| US-9701700-B2 | Process for the preparation of acylphosphanes | ETH ZUERICH (CH) | 2017-07-11 | — | — | US | disclosed |
| US-20150299231-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH ZUERICH (CH) | 2015-10-22 | — | — | US | disclosed |
| EP-2903995-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH Zürich (CH) | 2015-08-12 | — | — | EP | disclosed |
| WO-2014053455-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | ETH Zürich (CH) | 2014-04-10 | — | — | WO | disclosed |
| US-6114582-A | DECYCLIZATION TO FORM A CHEMICAL INTERMEDIATE FOR PRODUCING AN ANTI-OBESITY AGENT AND ANTIDIABETIC AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0654534-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2000-03-01 | — | — | EP | disclosed |
| EP-0939134-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-01 | — | — | EP | disclosed |
| EP-0924193-A1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| EP-0924194-A2 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| US-5629200-A | MICROORGANISM | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0441979-B1 | OPTICALLY ACTIVE 2-(ALKYL-SUBSTITUTED PHENYL)-PROPIONIC ACID DERIVATIVE AND OPTICAL RESOLUTION OF ( )-1-METHYL-3-PHENYLPROPYLAMINE | DAICEL CHEM (JP) | 1996-01-31 | — | — | EP | disclosed |
| EP-0654534-A2 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-24 | — | — | EP | disclosed |
| EP-0441979-A1 | OPTICALLY ACTIVE 2-(ALKYL-SUBSTITUTED PHENYL)-PROPIONIC ACID DERIVATIVE AND OPTICAL RESOLUTION OF ( )-1-METHYL-3-PHENYLPROPYLAMINE | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1991-08-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10273258-B2 | Process for the preparation of acylphosphanes | AGPAT5, AGPAT2, PHOSPHO1 | PTGS2 1292/4885KDM4E 2609/4885TPMT 786/4885 |
| US-20180002357-A1 | PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | AGPAT5, AGPAT2, PHOSPHO1 | PTGS2 1292/4885KDM4E 2609/4885TPMT 786/4885 |
| US-20150299231-A1 | A PROCESS FOR THE PREPARATION OF ACYLPHOSPHANES | AGPAT5, PHOSPHO1, AGPAT2 | PTGS2 1480/4885KDM4E 2878/4885TPMT 804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.