Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21268965 | 0.98 | KDM4E (0.41) | KDM4ETPMTALDH1A1IGFBP3SLC6A2 | |
| SCHEMBL21269629 | 0.98 | KDM4E (0.41) | KDM4ETPMTALDH1A1IGFBP3SLC6A2 | |
| SCHEMBL21269842 | 0.98 | KDM4E (0.41) | KDM4ETPMTALDH1A1IGFBP3SLC6A2 | |
| SCHEMBL28016266 | 0.89 | KDM4E (0.38) | KDM4ETPMTALDH1A1IGFBP3SLC6A2 | |
| SCHEMBL6838455 | 0.87 | ALDH1A1 (0.42) | KDM4ETPMTALDH1A1IGFBP3CA1 | |
| SCHEMBL6839567 | 0.86 | ALDH1A1 (0.37) | KDM4ETPMTALDH1A1IGFBP3SLC6A2 | |
| SCHEMBL15841100 | 0.86 | KDM4E (0.37) | KDM4ETPMTALDH1A1IGFBP3SLC6A2 | |
| SCHEMBL6838447 | 0.82 | ALDH1A1 (0.36) | KDM4EALDH1A1SRCTDP1HPGD | |
| SCHEMBL14490811 | 0.81 | ALDH1A1 (0.38) | KDM4ETPMTALDH1A1IGFBP3SLC6A2 | |
| SCHEMBL6807941 | 0.81 | KDM4E (0.42) | KDM4ETPMTALDH1A1IGFBP3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868714-B2 | Pyrone compounds and herbicides comprising the same | SUMITOMO CHEMICAL COMPANY (JP) | 2018-01-16 | — | — | US | disclosed |
| US-9868714-B2 | Pyrone compounds and herbicides comprising the same | SUMITOMO CHEMICAL COMPANY (JP) | 2018-01-16 | — | — | US | disclosed |
| EP-2906557-B1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL CO (JP) | 2016-11-30 | — | — | EP | disclosed |
| US-20150274691-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2015-10-01 | — | — | US | disclosed |
| US-20150274691-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2015-10-01 | — | — | US | disclosed |
| WO-2014058037-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-04-17 | — | — | WO | disclosed |
| US-20040198797-A1 | Process for the preparation of herbicidal derivatives | MAETZKE THOMAS (CH) | 2004-10-07 | — | — | US | disclosed |
| EP-1183317-B1 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-6552187-B1 | Cyclization condensation of arylmalonic acid diamides or arylmalonic acid monoamides with hydrazine derivatives forming substituted 3-hydroxy-4-aryl-5-oxopyrazolines; high yield and purity | SYNGENTA CROP PROTECTION, INC. | 2003-04-22 | — | — | US | disclosed |
| EP-1185506-A1 | SUBSTITUTED ARYLMALONIC ACID DINITRILES AS INTERMEDIATES FOR THE PREPARATION OF HERBICIDES | Syngenta Participations AG (CH) | 2002-03-13 | — | — | EP | disclosed |
| EP-1183317-A2 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | Syngenta Participations AG (CH) | 2002-03-06 | — | — | EP | disclosed |
| WO-2000078712-A1 | SUBSTITUTED ARYLMALONIC ACID DINITRILES AS INTERMEDIATES FOR THE PREPARTION OF HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000078881-A2 | PROCESS FOR THE PREPARATION OF HERBICIDAL DERIVATIVES | SYGENTA PARTICIPATIONS AG (CH) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274691-A1 | PYRONE COMPOUNDS AND HERBICIDES COMPRISING THE SAME | CBR3, NOTUM, DDT | KDM4E 310/4885TPMT 1118/4885ALDH1A1 1109/4885 |
| US-20040198797-A1 | Process for the preparation of herbicidal derivatives | CBR3, CBR1, CYC1 | KDM4E 2182/4885TPMT 3499/4885ALDH1A1 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.