Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | EBP | Q15125 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5994591 | 0.89 | CYP3A4 (0.39) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL6403712 | 0.85 | HTR1D (0.34) | HPGD | |
| SCHEMBL5994805 | 0.82 | ALDH1A1 (0.35) | CYP3A4SMN1; SMN2KMT2A | |
| SCHEMBL5996433 | 0.82 | KDM4E (0.37) | MAPK1SMN1; SMN2LMNAHPGDKMT2A | |
| SCHEMBL5993302 | 0.78 | TP53 (0.46) | SMN1; SMN2LMNAHPGDABCG2KMT2A | |
| SCHEMBL6399268 | 0.74 | CYP3A4 (0.40) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL5997609 | 0.74 | CYP3A4 (0.38) | CYP3A4USP2MAPK1SMN1; SMN2HPGD | |
| SCHEMBL5996238 | 0.74 | CYP3A4 (0.38) | CYP3A4USP2MAPK1SMN1; SMN2CYP2D6 | |
| SCHEMBL6396397 | 0.74 | TP53 (0.43) | SMN1; SMN2LMNAHPGDABCG2KMT2A | |
| SCHEMBL5995238 | 0.72 | CYP3A4 (0.36) | CYP3A4USP2MAPK1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969733-B2 | Photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-11-29 | — | — | US | disclosed |
| US-20030139485-A1 | Photoinitiators | WOLF JEAN-PIERRE (CH) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139485-A1 | Photoinitiators | DHCR24, NR1I3, CBR1 | CYP3A4 432/4885USP2 4345/4885MAPK1 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.