Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5994596 | 0.90 | CYP3A4 (0.41) | CYP3A4USP2MAPK1SMN1; SMN2ABCG2 | |
| SCHEMBL6403714 | 0.84 | POLB (0.38) | HPGDKMT2AMEN1TSHR | |
| SCHEMBL5994813 | 0.83 | ALDH1A1 (0.36) | CYP3A4SMN1; SMN2KMT2AKDM4EMEN1 | |
| SCHEMBL5996436 | 0.79 | RXRB (0.37) | SMN1; SMN2HPGDKMT2AKDM4EMEN1 | |
| SCHEMBL5993310 | 0.78 | NPC1 (0.48) | CYP3A4SMN1; SMN2ABCG2HPGDKMT2A | |
| SCHEMBL5996227 | 0.75 | CYP3A4 (0.39) | CYP3A4USP2MAPK1SMN1; SMN2ABCG2 | |
| SCHEMBL6399267 | 0.74 | CYP3A4 (0.37) | CYP3A4USP2MAPK1SMN1; SMN2ABCG2 | |
| SCHEMBL6396405 | 0.74 | NPC1 (0.44) | ABCG2HPGDKMT2AMEN1MAPT | |
| SCHEMBL2499311 | 0.72 | KDM4E (0.41) | MAPK1SMN1; SMN2HPGDKMT2AKDM4E | |
| SCHEMBL7181484 | 0.71 | CYP3A4 (0.38) | CYP3A4USP2MAPK1SMN1; SMN2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6969733-B2 | Photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-11-29 | — | — | US | disclosed |
| US-20030139485-A1 | Photoinitiators | WOLF JEAN-PIERRE (CH) | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139485-A1 | Photoinitiators | DHCR24, NR1I3, CBR1 | CYP3A4 432/4885USP2 4345/4885MAPK1 1788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.