Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.47 |
| ▸ | CDC25A | P30304 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20996294 | 0.92 | CDC25A (0.42) | CDC25BCDC25APTPN1 | |
| SCHEMBL20996200 | 0.79 | TSHR (0.38) | CDC25BCDC25AMEN1KMT2A | |
| SCHEMBL20996213 | 0.79 | ADRA2A (0.35) | CDC25BCDC25AMEN1KMT2A | |
| SCHEMBL28446636 | 0.78 | TSHR (0.37) | CDC25BCDC25AMEN1KMT2A | |
| SCHEMBL28441421 | 0.78 | TSHR (0.37) | CDC25BCDC25AMEN1KMT2A | |
| SCHEMBL20996240 | 0.77 | SMN1; SMN2 (0.33) | CDC25BCDC25A | |
| SCHEMBL28441415 | 0.75 | TSHR (0.35) | CDC25BCDC25A | |
| SCHEMBL20996296 | 0.74 | TSHR (0.34) | CDC25BCDC25A | |
| SCHEMBL20996267 | 0.74 | TSHR (0.34) | CDC25BCDC25A | |
| SCHEMBL3899596 | 0.71 | CDC25A (0.60) | CDC25BCDC25APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774253-B1 | REACTING TITANIUM HALIDE OR ALKYLATE WITH LIGAND, GRIGNARD REAGENT OR ORGANIC ALKALI METAL COMPOUND; COMPLEXING; METALLIZATION; OLEFIN POLYMERIZATION CATALYSTS | BASELL POLYOLEFINE GMBH (DE) | 2004-08-10 | — | — | US | claimed |
| EP-1102778-B1 | PROCESS FOR THE PREPARATION OF TITANIUM COMPLEXES | BASELL POLYOLEFINE GMBH (DE) | 2003-04-02 | — | — | EP | claimed |
| US-6500949-B2 | ALPHA-OLEFIN POLYMERIZATION CATALYST | DOW GLOBAL TECHNOLOGIES INC. | 2002-12-31 | — | — | US | claimed |
| US-6388118-B1 | Process for the preparation of cyclopentadienyl compounds and compounds obtained therefrom | BASELL TECHNOLOGY COMPANY BV (NL) | 2002-05-14 | — | — | US | claimed |
| US-20010025115-A1 | Bridged metal complexes | DOW GLOBAL TECHNOLOGIES LLC | 2001-09-27 | — | — | US | claimed |
| EP-1102778-A1 | PROCESS FOR THE PREPARATION OF TITANIUM COMPLEXES | Basell Technology Company B.V. (NL) | 2001-05-30 | — | — | EP | claimed |
| WO-2000075151-A1 | PROCESS FOR THE PREPARATION OF TITANIUM COMPLEXES | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2000-12-14 | — | — | WO | claimed |
| CN-1272852-A | Process for preparing ethylene and alpha-olefin copolymer | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-11-08 | — | — | CN | claimed |
| CN-112154163-B | Transition metal compound and method for preparing polypropylene using the same | LG化学株式会社 | 2022-12-27 | — | — | CN | disclosed |
| CN-111417657-B | Asymmetric ansa-metallocene catalyst compounds for the preparation of polyolefins having broad molecular weight distribution | 埃克森美孚化学专利公司 | 2022-11-25 | — | — | CN | disclosed |
| US-10889663-B2 | Asymmetric ANSA-metallocene catalyst compounds for producing polyolefins having a broad molecular weight distribution | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2021-01-12 | — | — | US | disclosed |
| CN-112154163-A | Novel transition metal compound and method for preparing polypropylene using the same | LG化学株式会社 | 2020-12-29 | — | — | CN | disclosed |
| CN-111417657-A | Asymmetric ansa-metallocene catalyst compounds for the preparation of polyolefins having broad molecular weight distribution | 埃克森美孚化学专利公司 | 2020-07-14 | — | — | CN | disclosed |
| US-20190161560-A1 | Asymmetric ANSA-Metallocene Catalyst Compounds for Producing Polyolefins Having a Broad Molecular Weight Distribution | EXXONMOBIL CHEMICAL PATENTS INC. | 2019-05-30 | — | — | US | disclosed |
| CN-1277618-A | Process for the preparation of substantially amorphous alpha-olefin polymers, compositions containing them and process for the preparation of bridged ligand | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-12-20 | — | — | CN | disclosed |
| WO-2000075151-A1 | PROCESS FOR THE PREPARATION OF TITANIUM COMPLEXES | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2000-12-14 | — | — | WO | disclosed |
| CN-1272852-A | Process for preparing ethylene and alpha-olefin copolymer | MONTELL TECHNOLOGY COMPANY BV (NL) | 2000-11-08 | — | — | CN | disclosed |
| WO-2000020462-A2 | BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS | BP CHEMICALS LIMITED (GB) | 2000-04-13 | — | — | WO | disclosed |
| WO-2000020426-A1 | BRIDGED METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2000-04-13 | — | — | WO | disclosed |
| CN-1150430-A | Metallocene compound, preparation method thereof and application thereof in olefin polymerization catalyst | MONTELL TECHNOLOGY COMPANY BV (NL) | 1997-05-21 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010025115-A1 | Bridged metal complexes | SLC39A14, NBAS, MCM4 | CDC25B 769/4885CDC25A 960/4885PTPN1 4455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.