SCHEMBL6399290

SCHEMBL6399290

COC(C)(NC(=O)O)OC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
DGAT1 O75907 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5745453 0.97 ALDH1A1 (0.32) ALDH1A1DGAT1TSHR
SCHEMBL1931460 0.82
SCHEMBL5745449 0.76 ALDH1A1 (0.32) ALDH1A1DGAT1
SCHEMBL6759439 0.76 CRBN (0.32) ALDH1A1DGAT1TSHR
SCHEMBL7827751 0.76 ALDH1A1 (0.32) ALDH1A1DGAT1
Oxalic Acid SCHEMBL7867005 0.72 TSHR (0.35) ALDH1A1DGAT1TSHR
SCHEMBL28207423 0.70 ALDH1A1 (0.42) ALDH1A1
SCHEMBL8826965 0.70 ALDH1A1 (0.34) ALDH1A1
SCHEMBL28707490 0.69 TSHR (0.39) ALDH1A1TSHR
SCHEMBL9253 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6967196-B1 Sulfonamide compounds and uses thereof BRISTOL-MYERS SQUIBB COMPANY (US) 2005-11-22 US disclosed
CN-1091135-A The carbamate of Wyeth-Ayerst Laboratories AMERICAN HOME PROD (US) 1994-08-24 CN disclosed