SCHEMBL28707490

SCHEMBL28707490

CC(C)(NC(=O)O)C(C)(C)NC(=O)O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
NAALAD2 Q9Y3Q0 1/20 0.32
HMGCR P04035 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
ADRA1A P35348 1/20 0.32
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
KDM4C Q9H3R0 1/20 0.31
EPHX1 P07099 1/20 0.31
CYP2D6 P10635 1/20 0.30
CYP2C19 P33261 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23571 0.82 PDK1 (0.32) TSHRALDH1A1
SCHEMBL738576 0.82 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL30130704 0.80
SCHEMBL9253 0.79
SCHEMBL20206689 0.78 PIK3CD (0.34) CYP2D6CYP2C19
Hydrochloric Acid SCHEMBL9158754 0.76
Ammonia Solution, Strong SCHEMBL1793738 0.76 EPHX1 (0.40) TSHRALDH1A1EPHX1
SCHEMBL2825781 0.76
Water SCHEMBL6698331 0.76
SCHEMBL9065833 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114269794-A Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2022-04-01 CN disclosed